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Lesson note
Acid–base balance
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Diagram · step 2 of 4
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Sample
Physiology · Acid–base · Lesson note
Why does persistent vomiting make you alkalotic?
Parietal cells secrete H⁺ into the stomach and send HCO₃⁻ into the blood. The pancreas later neutralises the acid, so the two cancel.
Vomiting throws the H⁺ and Cl⁻ away, so the bicarbonate in the blood is never cancelled. The lost volume drives aldosterone, which makes the kidney trade Na⁺ for H⁺ and K⁺.
Metabolic alkalosis, with low chloride and low potassium, and an acid urine.
“Acidosis, because fluid is lost.” That is diarrhoea, which loses bicarbonate.
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Compare · Sample
What is lostH⁺ and Cl⁻
The blood becomesAlkalotic
ChlorideLow
PotassiumLow
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RevisionDue today
Brachial plexus3 due
Acid–base5 due
Glycolysis control2 due
Knee ligaments4 due
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Lesson notes · MBPrep
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